一、基本情况介绍

杨如洁，女，讲师，博士研究生，毕业于澳门大学。

二、教学工作

承担基础化学,无机化学理论和实验教学等工作。

三、科研工作

1、主持或参加科研项目

[1] 基于点击化学策略的羧基代谢物富集分析方法的构建及II型糖尿病靶向标志物的发现，澳门大学研究资助基金, MYRG 2022-00020-ICMS, 2023-01至2024-12,45.675万元，在研，参与

[2] 功能模块化光动力药物用于克服非小细胞肺癌旁路激活耐药及序贯疗效监控，国家自然科学基金委员会与澳门科学技术发展基金联合科研资助基金项目，2021-10至2024-10,400万元，在研，参与

[3] Alleviate effects of long chain n-3 polyunsaturated fatty acids against acetaminophen-induced liver injury，澳门科学技术发展基金，FDCT 0065/2018/A2，2018-10至2020-10，101.2万元，结题，参与

2、代表性论著

[1]  Rujie Yang, Jian Zou, Jia-Yue Liu, Jiang-Kun Dai, Jian-Bo Wan^*, Click chemistry-based enrichment strategy for tracing cellular fatty acid metabolism by LC-MS/MS. Journal of Pharmaceutical Analysis. 2023.05.001.

[2] Rujie Yang, Fangbo Xia, Huanxing Su, Jian-Bo Wan^*, Quantitative analysis of n-3 polyunsaturated fatty acids and their metabolites by chemical isotope labeling coupled with liquid chromatography – mass spectrometry. Journal of Chromatography B. 2021.122666.

[3] Rujie Yang, Yingchao Li, Jing Li, Cuiru Liu, Ping Dua and Tianhong Zhang*, Application of scCO2 technology for preparing CoQ10 solid dispersion and SFC-MS/MS for analyzing in vivo bioavailability, Drug Development and Industrial Pharmacy. 2017.1391833.

[4] Rujie Yang, Yingchao Li, Cuiru Liu, Youjun Xu, Tianhong Zhang^*, An improvement of separation and response applying post-column compensation and one-step acetone protein precipitation for the determination of coenzyme Q10 in rat plasma by SFC-MS/MS. Journal of Chromatography B. 2016.07.050.

[5] Jian Zou, Rujie Yang, Jia-Yue Liu, Jiang-Kun Dai, Jian-Bo Wan*, Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways in mice Journal of Pharmaceutical Analysis. 2023.05.005.